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Experience profound heart-opening and clarity through sacred medicine work with experienced facilitators in safe, legal settings

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Top Bufo Retreats

Entheo-weekends in Eco-Lodge Tulum

Top Rated iconTop Rated
Date Flexible Dates
Center Xanga Guru Experiences Ciudad Chemuyil, Mexico

Anonymous says, "I had a lovely experience and valued the subtleties of ayahuasca with facilitator Agustina. As a 58 year old woman, I enjoyed the evening in an amazing setting where I quietly explored and deepened my relationship between myself and the great mother earth." See more

From $730
4.94
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3 Night Bufo Alvarius (5 MeO DMT) and Psilocybin Mushroom Retreat

Best Seller iconBest Seller
Date May 29 - June 1, 2025
Center Arkana Spiritual Center Valle de Bravo, Mexico

Anonymous says, "I had a transformative experience at Arkana Spiritual Center. Each day surprised me with a feeling of more connection to my true self, information for me to continue growing and a the feeling of vibrating on a higher frequency." See more

From $1,980 / 4 days
5.00
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Bufo Alvarius Ceremony in Barcelona, Spain

Kerilyn 's Staff Pick iconKerilyn 's Staff Pick
Date March 21, 2025
Center weareavalon.love Barcelona, Spain

Sarah says, "He tenido la suerte de trabajar con los Magic Mushroom y ha sigo una experiencia mรกgica. El equipo acompaรฑan de la mejor manera posible. Lo recomiendo 100%" See more

โ‚ฌ359 / 1 day
4.97
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Private Bufo Alvarius ceremonies for individuals, couples and groups, Tenerife, Spain

Date Open Dates
Center Safe Spirit Canary Islands, Spain

Anonymous says, "I am so glad I went on this retreat. The revelation/takeaway I got from the plant medicineโ€™s was that it showed me that there is a lot of peace and love deep inside of me." See more

$175
4.79
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5-Day Bufo Retreat in Portugal: Deep Healing with Non-Dual Coaching & Trauma Release

Last Chance iconLast Chance
Date March 3 - 9, 2025
Center Shangriballa Colmeal, Portugal

Goda says, "It was my first experience with retreat guru, with kambo and with bufo. Lots of first times. I was not disappointed. I felt taken care of, Lisa was very welcoming, clear, helped with all my questions before and during the stay." See more

From โ‚ฌ1,400 / 7 days
5.00
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Triple Sourced Bufo/DMT and Psilocybin Experience- Cancun

Date February 22 - 24, 2025
Center Bernice Andersen IXCA Cancรบn, Mexico

Michelle says, "I feel that this was the best retreat for me for what I was seeking. I wanted to feel connected, seen, heard, and loved. I was looking for healing with a nurturing, strong, loving group of guides." See more

From $444 / 3 days
5.00
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Private Bufo Alvarius / 5-MeO-DMT Ceremony in Mazunte

Date Open Dates
Center Bufo Alvarius Retreats Mazunte, Mexico

Taylor says, "Thanks to Isa for creating the perfect space for transformation, while allowing the guest the freedom to have their own moments with god. Iโ€™m already planning my next trip to see her down in Mazunte and strongly recommend her guidance and powerful presence to any seeking a deeply profound experience!" See more

From $495
5.00
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Kambo, Bufo Alvarius and Floatation with magic mushroom in Tulum

Date 4 Days Package

Ogadinma says, "There are no words, only love. " See more

From $900
4.94
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Date Flexible Dates
Center Shakti Healing. Sacred Medicine Provincia de Guanacaste, Costa Rica

Anonymous says, "Sole is a beautiful soul and made the entire experience go smoothly and safely for me. Grateful that I had the opportunity to experience this!" See more

$240
5.00
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Bufo Alvarious (5MEO-DMT)Expansive Experince in Playa del Carmen

Date Open Dates

Roxana says, "She is very loving, warm and transmits a lot confidence. Clau guided my process making me feel safe. After finishing the session, he offered me integration sessions after the bufo ceremony." See more

$169
5.00
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5-MEO DMT Bufo Alvarius Ceremony

Date Open Dates

Chandler says, "I had an amazing time at Espiral retreats working with Gary and Theo. Everything was tuned in to the highest degree, and offered everything we needed to have a safe, enjoyable, and transformative experience." See more

$200
5.00
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Bufo Alvarius Ceremony in Tulum

Date Flexible Dates
Center Sacred Heart Sonora Tulum, Mexico

Philippe says, "A Very profound experience! I definitely suggest it. Kate and Dr. G are incredible hosts. I felt the love and compassion. I have seen plenty of YouTube's that the person conducting looks unprofessional, you never know what could happen, nothing like having a medical doctor present incase something goes wrong." See more

From $400
5.00
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Bufo Stories

Questions about Bufo

What's the difference between Bufo and 5-MeO-DMT?

Toggle answer

Bufo and synthetic 5-MeO-DMT contain the same primary active compound, yet come from very different sources. Bufo refers to the natural secretions of the Sonoran Desert Toad (Bufo alvarius/Incilius alvarius), which indigenous peoples have worked with ceremonially for generations. These secretions contain 5-MeO-DMT along with other compounds like bufotenin. Synthetic 5-MeO-DMT, in contrast, is a pure laboratory-created substance containing only the single molecule. Many traditional practitioners prefer working with Bufo for its complete, natural medicine profile, though this raises serious ecological concerns about toad populations. The synthetic form allows for precise dosing and helps protect these sacred creatures from over-harvesting, while still offering profound experiences when approached with proper respect and guidance. The choice between them often comes down to personal values around tradition versus sustainability, though their effects are remarkably similar when administered with equal care and reverence.

What are the side effects of the Bufo or 5-MeO-DMT?

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Within moments of administration, users typically experience rapid heart rate, increased blood pressure, and intense physical sensations that some describe as a "system reboot." Physical side effects often include nausea, disorientation, difficulty with motor coordination, and sometimes tremors or muscle tension. These acute effects usually last 15-20 minutes, though some people report lingering physical sensitivity for several hours afterward.

The psychological effects can be profound and sometimes challenging. Many experience complete dissolution of ego boundaries, which some find deeply liberating while others find terrifying. In sacred contexts, this medicine has been known to trigger overwhelming emotions, memory recall, and occasionally temporary confusion about one's identity or reality. Integration challenges may persist for days or weeks, particularly for those without proper support or preparation. Some retreat centers report that participants occasionally experience temporary anxiety, sleep disruptions, or shifts in mood during the integration period.

Traditional practitioners emphasize that these aren't merely "side effects" but rather aspects of a holistic healing process that requires proper ceremonial container, experienced facilitation, and thorough medical screening. Certain medical conditions and medications can create dangerous interactions - particularly heart conditions, high blood pressure, or psychiatric medications.

How long do ayahuasca effects last?

Toggle answer

The effects of ayahuasca typically unfold across distinct phases over 4-6 hours, though the full journey can last up to 8 hours for some people. Traditional Amazonian ceremonies usually begin in the evening and continue through the night, with the most intense period occurring 1-2 hours after drinking the medicine. The physical effects often start within 30 minutes, while the visionary phase commonly peaks between hours 2-4. After the main journey subsides, many experience a gentle "landing" period of 1-2 hours where insights continue to emerge. In traditional contexts, integration begins immediately after the ceremony and extends for days or weeks - this is considered an essential part of the medicine's work. Some retreat centers observe that certain participants may feel subtle energetic shifts for several days following a ceremony, though these are typically mild and manageable. Each person's experience with the medicine follows its own timing and rhythm. Traditional healers emphasize that the effects aren't limited to the ceremonial hours - rather, the ceremony opens a door through which healing and understanding continue to flow long after the acute effects have passed.